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The time has come to use metabolomics in clinical settings. Such metabolite data is used for diagnosing subtypes of patient groups, to understand the mechanisms of the onset and progression of diseases, and to be used in the context of Precision Medicine. Led by UC Davis researchers, more than 1,000 identified metabolites are now routinely screened in plasma, tissue, urine or cell samples. Metabolomics has matured over the past 20 years.